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pentobarbital will lower the extent or outcome of ramelteon by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.pentobarbital will lower the level or result of isavuconazonium sulfate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.pentobarbital will lower the extent or result of estroge